In 2010,only one year after the events of Resident Evil 5, a misterious attack was made to the B.S.A.A.´s Arican head-quarters. After the security camara videos were analized, the other B.S.A.A. members realised that this attack was made by a former member of the B.S.A.A. who was supposed to be dead, Tomé Laga. His demands were unknown, as his motives for making the attack. Also, they realised that he had several t-virus samples, and that he released one in the head-quarters. Fearing another outbrake, they sent after Tomé Chris Redfield, Jill Valentine, Sheva Alomar and Josh Stone. After this, Tomé released a video stating that the B.S.A.A. wouldn´t be able to stop all the outbrakes that he was about to create. At first, they tracked him down to Australia, where they encountered the first t-virus outbrake. Then, they tracked him down to Japan, where a second outbrake was caused again by Tomé Laga. Finally, they tracked him down to Canada, where a third outbrake was caused once more by Tomé. There, they had a face-to-face encounter with Tomé Laga, and they soon realised that he was infected with a new virus, the G-Veronica virus. After a tough and long fight, Tomé escaped, but before, he killed Josh Stone. After that, they all tracked him down to Africa. In there, they found out that the U.S. Goverment had also sent an agent to capture Tomé, Leon S. Kennedy.
Despite the fact that they were the best agents in the world, they still were not able to catch Tomé.